Supercooling extends preservation time of human livers
نویسندگان
چکیده
منابع مشابه
Supercooling as a Viable Non-Freezing Cell Preservation Method of Rat Hepatocytes
Supercooling preservation holds the potential to drastically extend the preservation time of organs, tissues and engineered tissue products, and fragile cell types that do not lend themselves well to cryopreservation or vitrification. Here, we investigate the effects of supercooling preservation (SCP at -4(o)C) on primary rat hepatocytes stored in cryovials and compare its success (high viabili...
متن کاملSuccessful cryopreservation of human ovarian cortex tissues using supercooling
The development of new method to cryopreserve human ovarian cortex tissues without damage is needed for the improvement of quality of life (QOL) of female cancer patients. Here we show novel cryopreservation method of human ovarian cortex tissues by using supercooling (S.C.) procedure. Our method will be helpful in order to preserve fertility of female cancer patients.
متن کاملContinuous perfusion of donor hearts in the beating state extends preservation time and improves recovery of function.
OBJECTIVES Improving methods of donor heart preservation may permit prolonged storage and remote procurement of cardiac allografts. We hypothesized that continuous, sanguineous perfusion of the donor heart in the beating, working state may prolong myocardial preservation. METHODS We developed a portable perfusion apparatus for use in donor heart preservation. Contractile, metabolic, and vasom...
متن کاملADDENDUM: Successful cryopreservation of human ovarian cortex tissues using supercooling
Editorial Note: Successful cryopreservation of human ovarian cortex tissues using supercooling Scientific Reports has become aware of irregularities related to authors affiliations and the statement describing IRB approval in this paper. The situation is being investigated.
متن کاملThe Sampling and Analysis of Human Livers
A comprehensive approach to the analysis of human livers has been developed in a pilot program for a National Environmental Specimen Bank (NESB). Since 1980, the pilot NESB program has examined the collection, processing, storage and analysis of human livers. Sampling protocols, handling procedures and analytical methods have been developed and implemented considering the requirements for valid...
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ژورنال
عنوان ژورنال: Nature Biotechnology
سال: 2019
ISSN: 1087-0156,1546-1696
DOI: 10.1038/s41587-019-0223-y